Bupropion (INN; also amfebutamone,[1] brand names Wellbutrin and Zyban) is an antidepressant of the aminoketone class, chemically unrelated to tricyclics or selective serotonin reuptake inhibitors (SSRIs). It is similar in structure to the stimulant cathinone, and to phenethylamines in general. It is a chemical derivative of diethylpropion, an amphetamine-like substance used as an anorectic. Bupropion is both a dopamine reuptake inhibitor and a norepinephrine reuptake inhibitor.[2] It is used as a smoking cessation aid under the brand name Zyban, and as an antidepressant under the brand name Wellbutrin, Wellbutrin SR and Wellbutrin XL.

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